lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2

Table 1 Quantitative analysis of lethal and mitotic phenotypes of lmg mutants

Genotype	Lethal phase	Preparations per fields	Mitotic index	M:A ratio	Polyploid %	Apoptotic index
A
w ¹¹¹¹⁸	Viable	7/183	1.6 ± 0.2	2.9 ± 0.3	0	0.5 ± 0.1
lmg ⁰³⁴²⁴	Pharate adult P15(i)	6/135	4.1 ± 0.8	4.5 ± 0.7	19.6 ± 5.6	1.4 ± 0.3
lmg ^J023	Pupal stage P5(i)	7/167	4.4 ± 0.9	6.3 ± 0.1	29.1 ± 7.4	1.2 ± 0.2
lmg ^EY11317	Prepupal stage P4(ii)	6/170	5.8 ± 0.7	6.2 ± 0.4	26.6 ± 3.1	1.5 ± 0.4
lmg ¹³⁸	Prepupal stage P4(i)	10/194	5.9 ± 0.5	-	50.7 ± 7.9	1.8 ± 0.5
lmg ¹³⁸ ;lmgA- pUAST/daGAL4	Viable	6/180	1.5 ± 0.2	3 ± 0.6	0	0.5 ± 0.1
lmg ¹³⁸ ;lmgA + B- pUAST/daGAL4	Viable	4/100	1.4 ± 0.2	3.1 ± 0.3	0	0.6 ± 0.2
lmg ¹³⁸ ;lmgB- pUAST/daGAL4	Prepupal stage P4(i)	5/100	4.9 ± 0.9	-	43.7 ± 6.2	1.7 ± 0.2
B
mr ²	Female sterile	6/174	1.4 ± 0.1	3.3 ± 0.4	0	1.2 ± 0.3
lmg ⁰³⁴²⁴ , mr ²	Prepupal stage P4(ii)	6/106	4.5 ± 0.7	4.4 ± 0.3	31.8 ± 3.9	1.3 ± 0.4
C
vihar ^S110501	Pharate adult P15(i)	7/196	2.1 ± 0.3	3.7 ± 0.6	4.2 ± 0.4	0.9 ± 0.3
lmg ⁰³⁴²⁴ , vihar ^S110501	Bubble prepupa	6/116	6.1 ± 0.6	3.9 ± 0.7	44.3 ± 8.4	1.8 ± 0.3
	stage P3
mr ² ; vihar ^S110501	Early L3 larvae	n.d.	n.d.	n.d.	n.d.	n.d.
mr ² ; vihar ^KG02013	Early L3 larvae	n.d.	n.d.	n.d.	n.d.	n.d.

The number of preparations and the total number of optical fields analyzed are given. Mitotic index is given as the average number of mitotic cells in an optical field (± sd). Polyploid% represents the percentage of mitotic cells (± sd) with higher than two sets of chromosomes. Apoptotic index is given as the mean number of apoptotic cells in a microscope field (± sd).

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