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Table 3 Comparison of BrdU between control (pLKO.1) and treatment (shCDK4) groups

From: Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis

Cell line Vector 6 hr 12 hr 24 hr
   Mean* std P-value† Mean std P-value† Mean std P-value†
MCF10A pLKO.1 5.629 3.740 0.1124 2.669 0.956 0.3790 0.944 0.571 0.9577
  shCDK4 2.807 2.460   1.165 1.628   0.855 0.689  
MDA-MB-468 pLKO.1 1.619 0.614 0.7841 1.229 1.030 0.9942 6.503 7.950 0.0828
  shCDK4 0.842 0.915   1.208 0.946   1.254 1.685  
MDA-MB-231 pLKO.1 1.698 0.870 0.8941 1.578 1.634 0.1996 1.097 0.562 0.5523
  shCDK4 1.806 0.731   2.654 3.050   1.581 0.173  
  1. * Mean (standard deviation) of the fold change to no radiation.
  2. † P-value is for comparing in the mean fold change no radiation between control and treatment groups.