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Table 3 Comparison of BrdU between control (pLKO.1) and treatment (shCDK4) groups

From: Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis

Cell line

Vector

6 hr

12 hr

24 hr

  

Mean*

std

P-value†

Mean

std

P-value†

Mean

std

P-value†

MCF10A

pLKO.1

5.629

3.740

0.1124

2.669

0.956

0.3790

0.944

0.571

0.9577

 

shCDK4

2.807

2.460

 

1.165

1.628

 

0.855

0.689

 

MDA-MB-468

pLKO.1

1.619

0.614

0.7841

1.229

1.030

0.9942

6.503

7.950

0.0828

 

shCDK4

0.842

0.915

 

1.208

0.946

 

1.254

1.685

 

MDA-MB-231

pLKO.1

1.698

0.870

0.8941

1.578

1.634

0.1996

1.097

0.562

0.5523

 

shCDK4

1.806

0.731

 

2.654

3.050

 

1.581

0.173

 
  1. * Mean (standard deviation) of the fold change to no radiation.
  2. † P-value is for comparing in the mean fold change no radiation between control and treatment groups.
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Cell Division

ISSN: 1747-1028

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