Figure 5
From: Cohesin loading factor Nipbl localizes to chromosome axes during mammalian meiotic prophase
Schematic for Nipbl localization during mammalian meiotic prophase. Summary of our observations on Nipbl localization is illustrated together with the major component of AE/LE (Sycp3) and previously reported localization of the cohesin complexes containing different α-kleisin subunits (Rec8, Rad21 and Rad21L) during mouse meiotic prophase in spermatocytes and oocytes [30, 32–36]. Note that we do not argue co-localization of each molecule in sub-regions of the AE/LE or molecule-to-molecule interactions.