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Fig. 8 | Cell Division

Fig. 8

From: Microarray expression profile of mRNAs and long noncoding RNAs and the potential role of PFK-1 in infantile hemangioma

Fig. 8

Suppression of PFK-1 inhibits HemEC growth and migration and induces cell cycle arrest. a Quantitative PCR and b western blot analysis was used to confirm the suppression rate of PFK-1 with shRNAs in HemECs. c CCK-8 assay was used to determine the effects of shPFK-1 on HemEC proliferation. (d–f) Inhibition of PFKFB3 with shRNA induces HemEC cell cycle arrest in the G1 phase. (g–i) Transwell assays were performed to measure the effects of PFK-1 on HemEC migration (Magnification × 100). *P < 0.05, **P < 0.01, ***P < 0.001

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Cell Division

ISSN: 1747-1028

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