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Table 4 The association of TTK score with the clinical variables in the total cohort

From: Ethnic and racial-specific differences in levels of centrosome-associated mitotic kinases, proliferative and epithelial-to-mesenchymal markers in breast cancers

 

TTK expression = 0

TTK expression > 0

P-overall

N = 214

N = 191

Race

  

0.004

 Black

62 (52.1%)

57 (47.9%)

 

 White

41 (33.1%)

83 (66.9%)

 

Ethnicity

  

 < 0.001

 Non-Hispanics

103 (42.4%)

140 (57.6%)

 

 Hispanics

111 (68.5%)

51 (31.5%)

 

Race and ethnicity

  

 < 0.001

 Non-Hispanic Black

62 (52.1%)

57 (47.9%)

 

 Non-Hispanic White

41 (33.1%)

83 (66.9%)

 

 Hispanics

111 (68.5%)

51 (31.5%)

 

ER_PR_Her2

  

 < 0.001

 ER-/PR-/Her2-

35 (37.6%)

58 (62.4%)

 

 ER-/PR-/Her2 + 

13 (50.0%)

13 (50.0%)

 

 ER + PR + /Her2- or + 

89 (73.0%)

33 (27.0%)

 

 Others

77 (47.0%)

87 (53.0%)

 

Mean vimentin score:

  

0.010

 Vimentin expression = 0

158 (58.7%)

111 (41.3%)

 

 Vimentin expression > 0

43 (43.0%)

57 (57.0%)

 

Mean E-cadherin score

  

0.015

 E-cadherin expression = 0

120 (59.4%)

82 (40.6%)

 

 E-cadherin expression > 0

81 (46.3%)

94 (53.7%)

 

Mean Ki67 score

  

0.041

 Ki67 expression = 0

154 (56.4%)

119 (43.6%)

 

 Ki67 expression > 0

55 (44.7%)

68 (55.3%)

 
  1. Allred score of TTK was treated as the categorical variable as non-expression (Allred score = 0, n = 214) and expression (Allred score > 0, n = 191).The clinical variables include race, hormone receptors, and mean score of Vimentin, E-cadherin, and Ki67 biomarkers. P-values were derived from Chi-squared tests
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Cell Division

ISSN: 1747-1028

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