Fig. 3

SGO1 depletion increases the number of cells arrested in metaphase and anaphase within tumors. Representative images of primary tumors of NSG mice treated with MDA-MB-231 shRNA Control or shRNA SGO1 (a). Images were taken at 400X magnification (scale bars = 100 μm). A summary table shows the average of cells in each mitotic phase and p-Values (b). *p < 0.05, **p < 0.01, and ***p < 0.001 were considered statistically significant. A Student t-test (unpaired, two-tailed) was used to compare differences between groups. *p < 0.05, **p < 0.01, and ***p < 0.001 were considered statistically significant. N.S. stands for not significant