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Fig. 3 | Cell Division

Fig. 3

From: circRNA_0001006 predicts prognosis and regulates cellular processes of triple-negative breast cancer via miR-424-5p

Fig. 3

Interaction between circ_0001006 and miR-424-5p. A, B miR-424-5p was downregulated in tumor tissues (A) and showed a negative correlation with circ_0001006 (B). C Lower expression of miR-424-5p was significantly associated with the poorer overall survival of TNBC patients. D The knockdown of circ_0001006 suppressed the expression of miR-424-5p, which was reversed by the transfection of its inhibitor in MDA-MB-231 and HCC-1937 cells. E miR-424-5p negatively regulated the luciferase activity of circ_0001006 in MDA-MB-231 and HCC-1937 cells. Different letters indicate significant differences (P < 0.05)

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