Molecular mechanisms involved in regulating protein activity and biological function of MST3

Cell Division

Table 2 Regulators involved in modulation of MST3 kinase activity

Upstream kinase/regulator	Regulatory mode	Biological function	References
Cdk5	Phosphorylate MST3 at Ser79	Neuronal migration	[31]
PKA	Phosphorylate MST3b at Thr18		[32]
Caspase 3	Cleave MST3 at AETD³¹³G	Apoptosis	[22]
MO25	Bind with MST3		[34]
PP2A	Dephosphorylate and inactivate MST3	Cell migration	[35]
FAM40A	Dephosphorylate and inactivate MST3	Cell migration	[14]

ISSN: 1747-1028