Table 4 Compounds confirmed as the MST3 inhibitors
From: Molecular mechanisms involved in regulating protein activity and biological function of MST3
Category | MST3 inhibitor | IC50 (μM) | Reference |
|---|---|---|---|
Triazole diamines | CDK2 inhibitor III | 0.014 | [54] |
JNJ-7706621 | 1.3 | ||
Triazole amine | Dasatinib | 7.4 | |
Triazole phenol | TP fragment | 0.023 | |
Quinoline and quinazoline amines | Bosutinib | 0.003 | |
Saracatinib | 11 | ||
Pyrazoles | Danusertib | 0.16 | |
AT9283 | 0.46 | ||
Indolinones | Hesperadin | 0.01 | |
C16 | 0.019 | ||
Sunitinib | 0.21 | ||
Aminopyrimidine | PF-03814735 | 0.023 | |
Pyrazolopyrididine | PP-121 | 0.086 | |
Benzimidazole | CP-673451 | 0.26 |