Fig. 11

Metascape functional analysis of transcriptome profiles based on differently expressed genes. A Heatmap of Gene Ontology (GO) enriched terms colored by p-values. B Clustered network of GO enriched terms where color represent its cluster identity. A circle node represents each term, the size of node is proportional to the number of input genes fall under that term, and its color represent its cluster identity. C Clustered network of GO enriched terms colored by p-value, where terms containing more genes tend to have a more significant p-value. D Protein–protein interaction (PPI) network clustered to five most significant MCODE components form the PPI network