Fig. 1
From: Cancer radioresistance is characterized by a differential lipid droplet content along the cell cycle
Upper panel: (A-C) Lipid Droplet distribution and quantification along the cell cycle in human lung cells (H460). Middle panel: (D-F) Lipid Droplet distribution and quantification along the cell cycle in human bladder cancer cells (T24). Lower panel: (G) schematic representation of LD content in cells along the cell cycle phases and its relationship with cancer radioresistance; (H) Survival curves of synchronized H460 and T24 cells at different time-points irradiated with 6 Gy X-rays as assessed by clonogenic assays. The data represent the mean of three biological replicates ± SD. The clonogenic assay values were normalized to the T0 value, representing the late G1 phase. T0 was set as 1, and the subsequent time points (T4, T8, and T12) were compared to it. (* ≤ 0.05; ** ≤ 0.01; *** ≤ 0.001 and ****≤ 0.0001)