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Table 1

From: Fez1/Lzts1 a new mitotic regulator implicated in cancer development

TUMOR

DELETION

RESULTS

AFFECTED EXONS

PUTATIVE PROTEIN CODED IN-FRAME

Esophagus

156–1542

FS

Exons 1,2,3

Leucine Zip(-)

Esophagus

558–1715

IF

Exons 2,3

Leucine Zip(-)

Esophagus

558–1715

IF

Exons 2,3

Leucine Zip(-)

Esophagus

558–1715

IF

Exons 2,3

Leucine Zip(-)

Esophagus

156–1542

FS

Exons 1,2,3

Leucine Zip(-)

 

1402–1578

IF

Exon 3

Leucine Zip(+)

Prostate

1366–1641

IF

Exon 3

Leucine Zip(+)

 

1402–1578

IF

Exon 3

Leucine Zip(+)

ALL

1402–1578

IF

Exon 3

Leucine Zip(+)

Melanoma

1417–1515

IF

Exon 3

Leucine Zip(+)

 

1516–1584

IF

Exon 3

Leucine Zip(+)

  1. IF, in-frame; FS, frameshift; Leucine Zip(-), Lzts1 protein coded in-frame with Leucine zipper; Leucine Zip(+), Lzts1 protein without Leucine zipper. ALL (acute lymphoblastic leukemia)