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  1. Problems with whole-culture synchronization methods for the study of the cell cycle have led to the need for an analysis of protein content during the cell cycle of cells that have not been starved or inhibite...

    Authors: Stephen Cooper, Michelle Paulsen, Mats Ljungman, Dang Vu-Phan, Duyang Kim and Mariam Gonzalez-Hernandez
    Citation: Cell Division 2007 2:28
  2. The NIMA-related kinases represent a family of serine/threonine kinases implicated in cell cycle control. The founding member of this family, the NIMA kinase of Aspergillus nidulans, as well as the fission yeast ...

    Authors: Laura O'Regan, Joelle Blot and Andrew M Fry
    Citation: Cell Division 2007 2:25
  3. Completion of DNA replication before mitosis is essential for genome stability and cell viability. Cellular controls called checkpoints act as surveillance mechanisms capable of detecting errors and blocking c...

    Authors: Jordi Torres-Rosell, Giacomo De Piccoli and Luis Aragón
    Citation: Cell Division 2007 2:19
  4. In eukaryotic organisms, chromosomes are spatially organized within the nucleus. Such nuclear architecture provides a physical framework for the genetic activities of chromosomes, and changes its functional or...

    Authors: Haruhiko Asakawa, Tokuko Haraguchi and Yasushi Hiraoka
    Citation: Cell Division 2007 2:17
  5. Many meiosis-specific proteins in Schizosaccharomyces pombe contain coiled-coil motifs which play essential roles for meiotic progression. For example, the coiled-coil motifs present in Meu13 and Mcp7 are require...

    Authors: Ayami Ohtaka, Takamune T Saito, Daisuke Okuzaki and Hiroshi Nojima
    Citation: Cell Division 2007 2:14
  6. The cyclin kinase inhibitor p27kip1 acts as a potent tumor supressor protein in a variety of human cancers. Its expression levels correlate closely with the overall prognosis of the affected patient and often pre...

    Authors: Irina Nickeleit, Steffen Zender, Uta Kossatz and Nisar P Malek
    Citation: Cell Division 2007 2:13
  7. Movement through the cell cycle is controlled by the temporally and spatially ordered activation of cyclin-dependent kinases paired with their respective cyclin binding partners. Cell cycle events occur in a s...

    Authors: Jennifer A Perry and Sally Kornbluth
    Citation: Cell Division 2007 2:12
  8. Ubiquitin is a highly versatile post-translational modification that controls virtually all types of cellular events. Over the past ten years we have learned that diverse forms of ubiquitin modifications and o...

    Authors: Tanja Woelk, Sara Sigismund, Lorenza Penengo and Simona Polo
    Citation: Cell Division 2007 2:11
  9. In the quest for novel molecular mediators of glioma progression, we studied the regulation of FBXW 7 (hCDC 4/hAGO/SEL 10), its association with survival of patients with glioblastoma and its potential role as a ...

    Authors: Martin Hagedorn, Maylis Delugin, Isabelle Abraldes, Nathalie Allain, Marc-Antoine Belaud-Rotureau, Michelle Turmo, Claude Prigent, Hugues Loiseau, Andréas Bikfalvi and Sophie Javerzat
    Citation: Cell Division 2007 2:9
  10. DNA replication must be tightly controlled to prevent initiation of a second round of replication until mitosis is complete. So far, components of the pre-replicative complex (Cdt1, Cdc6 and geminin) were cons...

    Authors: Umasundari Sivaprasad, Yuichi J Machida and Anindya Dutta
    Citation: Cell Division 2007 2:8
  11. The Fbw7 ubiquitin ligase promotes the rapid degradation of several important oncogenes, such as cyclin E, c-Myc, c-Jun, and Notch. The two fission yeast homologs of Fbw7, pop1 and pop2, have previously been s...

    Authors: Markus Welcker and Bruce E Clurman
    Citation: Cell Division 2007 2:7
  12. "Natura non facit saltum" (nature makes no leap) the Latins used to say, meaning that nature does not like discontinuities. Cells make no exception and indeed any discontinuity in the DNA double helix is promp...

    Authors: Sofia Francia, Robert S Weiss and Fabrizio d'Adda di Fagagna
    Citation: Cell Division 2007 2:3
  13. Understanding how molecular motors generate force and move microtubules in mitosis is essential to understanding the physical mechanism of cell division. Recent measurements have shown that one mitotic kinesin...

    Authors: Megan T Valentine, Polly M Fordyce and Steven M Block
    Citation: Cell Division 2006 1:31
  14. Regulation of protein stability through the ubiquitin proteasome system is a key mechanism underlying numerous cellular processes. The ubiquitin protein ligases (or E3) are in charge of substrate specificity a...

    Authors: Damien Hermand
    Citation: Cell Division 2006 1:30
  15. Abp1, and the closely related Cbh1 and Cbh2 are homologous to the human centromere-binding protein CENP-B that has been implicated in the assembly of centromeric heterochromatin. Fission yeast cells lacking Ab...

    Authors: Alexandra M Locovei, Maria-Grazia Spiga, Katsunori Tanaka, Yota Murakami and Gennaro D'Urso
    Citation: Cell Division 2006 1:27
  16. Centrosomes are frequently amplified in cancer cells. Increased numbers of centrosomes can give rise to multipolar spindles in mitosis, and thereby lead to the formation of aneuploid daughter cells. However, w...

    Authors: Vlastimil Srsen and Andreas Merdes
    Citation: Cell Division 2006 1:26
  17. Cyclin-dependent kinase (CDK)4 is a master integrator that couples mitogenic and antimitogenic extracellular signals with the cell cycle. It is also crucial for many oncogenic transformation processes. In this...

    Authors: Laurence Bockstaele, Katia Coulonval, Hugues Kooken, Sabine Paternot and Pierre P Roger
    Citation: Cell Division 2006 1:25
  18. The 2006 Cold Spring Harbor Laboratory meeting on the Mechanisms and Models of Cancer was held August 16–20. The meeting featured several hundred presentations of many short talks (mostly selected from the abs...

    Authors: Andriy Marusyk and James DeGregori
    Citation: Cell Division 2006 1:24
  19. A high proliferative capacity of tumor cells usually is associated with shortened patient survival. Disruption of the RB pathway, which is critically involved in regulating the G1 to S cell cycle transition, i...

    Authors: Amel Dib, Timothy R Peterson, Laura Raducha-Grace, Adriana Zingone, Fenghuang Zhan, Ichiro Hanamura, Bart Barlogie, John Shaughnessy Jr and W Michael Kuehl
    Citation: Cell Division 2006 1:23
  20. The polypeptide ubiquitin is used in many processes as different as endocytosis, multivesicular body formation, and regulation of gene transcription. Conjugation of a single ubiquitin moiety is typically used ...

    Authors: Tom AM Groothuis, Nico P Dantuma, Jacques Neefjes and Florian A Salomons
    Citation: Cell Division 2006 1:21
  21. The identity of the DNA helicase(s) involved in eukaryotic DNA replication is still a matter of debate, but the mini-chromosome maintenance (MCM) proteins are the chief candidate. Six conserved MCM proteins, M...

    Authors: Tomás Aparicio, Arkaitz Ibarra and Juan Méndez
    Citation: Cell Division 2006 1:18
  22. Ubiquitination regulates a host of cellular processes and is well known for its role in progression through the cell division cycle. In budding yeast, cadmium and arsenic stress, the availability of sulfur con...

    Authors: Peter Kaiser, Ning-Yuan Su, James L Yen, Ikram Ouni and Karin Flick
    Citation: Cell Division 2006 1:16
  23. Cullin 4 (Cul4), a member of the evolutionally conserved cullin protein family, serves as a scaffold to assemble multisubunit ubiquitin E3 ligase complexes. Cul4 interacts with the Ring finger-containing prote...

    Authors: Qian Dai and Hengbin Wang
    Citation: Cell Division 2006 1:14
  24. Post-translational modifiers of the SUMO (S mall U biquitin-related M odifier) family have emerged as key regulators of protein function and fate. While the past few years have seen an enormous increase in knowle...

    Authors: Guillaume Bossis and Frauke Melchior
    Citation: Cell Division 2006 1:13

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  • 2022 Citation Impact
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    3.8 - 5-year Impact Factor
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